Anticancer Agents. Frontiers in Cancer Chemotherapy Cover

Anticancer Agents. Frontiers in Cancer Chemotherapy

ISBN/ASIN: 9780841237452,9780841218772,084123745X | 2001 | English | pdf | 375/375 pages | 32.4 Mb
Publisher: American Chemical Society | Author: Iwao Ojima, Gregory D. Vite, and Karl-Heinz Altmann (Eds.)

Content: Cancer drug discovery and development : new paradigms for a new millennium / E.A. Sausville … [et al.] —
Evolutionary biosynthesis of anticancer drugs / George R. Pettit —
Some recent developments in the synthesis and structure-activity relationship of novel taxanes / John F. Kadow … [et al.] —
New generation taxoids and hybrids of microtubule-stabilizing anticancer agents / Iwao Ojima … [et al.] —
Discodermolide and taxol : a synergistic drug combination in human carcinoma cell lines / Susan Band Horwitz … [et al.] —
Highly efficient semisynthesis of biologically active epothilone derivatives / Gregory D. Vite … [et al.] —
Synthetic and semisynthetic analogs of epothilones : chemistry and biological activity / Karl-Heinz Altmann … [et al.] —
Synthesis and biological activity of epothilones / Ulrich Klar … [et al.] —
Epothilones and sarcodictyins : from combinatorial libraries to designed analogs / Nicolas Winssinger and K.C. Nicolaou —
Synthesis and structure-activity relationship studies of cryptophycins : a novel class of potent antimitotic antitumor depsipeptides / Chuan Shih … [et al.] —
Farnesyltransferase inhibitors as potential anticancer agents / J.B. Gibbs … [et al.] —
Farnesyltransferase inhibitors : from squalene synthase inhibitors to the clinical agent BMS-214662 / John T. Hunt —
Inhibiting farnesyl protein transferase with Sch-66336 : potentially a selective noncytotoxic therapy for human cancer / A.G. Taveras … [et al.] —
Pyrrolo[2,3-d]pyrimidine and pyrazolo[3,4-d]pyrimidine derivatives as selective inhibitors of the EGF receptor tryosine kinase / G. Caravatti … [et al.] —
STI571 : a new treatment modality for CML? / Jürg Zimmermann, Pascal Furet, and Elisabeth Buchdunger —
The discovery and development of second-generation matrix metalloproteinase inhibitors for the treatment of cancer / Andy Baxter and John Montana —
Prospects for antiangiogenic therapies based upon VEGF inhibition / Pascal Furet and Paul W. Manley —
Carbohydrate-based tumor antigens as antitumor vaccine agents / Jennifer R. Allen and Samuel J. Danishefsky —
Drugs to enhance the therapeutic potency of anticancer antibodies : antibody-drug conjugates as tumor-activated prodrugs / Walter A. Blättler and Ravi V.J. Chari.

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