Textbook of Clinical Trials, Second Edition Cover

Textbook of Clinical Trials, Second Edition

ISBN/ASIN: 9780470010143,9780470010167 | 2006 | English | pdf | 741/741 pages | 7.14 Mb

Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume.
Praise for the First Edition:
"… very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005
The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area.  Specific examples are used throughout to address these issues.
The Textbook of Clinical Trials, Second Edition:  Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.Content:
Chapter 1 The Development of Clinical Trials (pages 1–11): Simon Day
Chapter 2 General Statistical Issues (pages 13–37): David Machin
Chapter 3 The Cochrane Collaboration (pages 39–46): Mike Clarke
Chapter 4 Breast Cancer (pages 47–61): Donald A. Berry, Terry L. Smith and Aman U. Buzdar
Chapter 5 Childhood Cancer (pages 63–80): Sharon B Murphy and Jonathan J. Shuster
Chapter 6 Gastrointestinal Cancers (pages 81–104): Daniel Sargent, Richard Goldberg and Paul Limburg
Chapter 7 Melanoma (pages 105–119): Ping?Yu Liu and Vernon K. Sondak
Chapter 8 Respiratory Cancers (pages 121–135): Joan H. Schiller and Kyungmann Kim
Chapter 9 Adrenal Cortical Carcinoma (pages 137–141): Isha Malik and Petros Perros
Chapter 10 Thyroid Cancer (pages 143–148): Vijayaraman Arutchelvam and Petros Perros
Chapter 11 Urologic Cancers (pages 149–165): Edith D. Canby?Hagino, Catherine M. Tangen and Ian M. Thompson
Chapter 12 Haematologic Cancers: Challenges in Developing New Therapeutic Approaches (pages 167–175): Charles A. Schiffer and Stephen L. George
Chapter 13 Acute Stroke (pages 179–214): Philip Bath
Chapter 14 Cardiovascular Disease (pages 215–239): Krishna Prasad
Chapter 15 Dentistry and Oral Health Care (pages 241–259): May C.M. Wong, Colman McGrath and Edward C.M. Lo
Chapter 16 Dermatology (pages 261–285): Luigi Naldi and Cosetta Minelli
Chapter 17 HIV Infection (pages 287–301): Michael D. Hughes
Chapter 18 Infectious Diseases (pages 303–315): Ingela Krantz
Chapter 19 Ophthalmology (pages 317–331): Jonathan C.K. Clarke and Peng?Tee Khaw
Chapter 20 Anxiety Disorders (pages 333–351): M. Katherine Shear and Philip W. Lavori
Chapter 21 Cognitive Behaviour Therapy (pages 353–376): Nicholas Tarrier and Til Wykes
Chapter 22 Psychotherapy for Depression (pages 377–393): Graham Dunn
Chapter 23 Contraception (pages 395–419): Gilda Piaggio and Timothy M. M. Farley
Chapter 24 Gynaecology and Infertility (pages 421–441): Siladitya Bhattacharya and Jill Mollison
Chapter 25 Early Pregnancy Termination (pages 443–457): Beverly Winikoff and Batya Elul
Chapter 26 Maternal and Perinatal Health (pages 459–473): Jose Villar, Allan Donner, Edgardo Abalos and Liana Campodonico
Chapter 27 Respiratory Medicine (pages 475–516): Anders Kallen
Chapter 28 Anaesthesia and Pain (pages 517–542): Paul S. Myles and John Rigg
Chapter 29 General Surgery (pages 543–552): Dr Olga Jonasson and Domenic Reda
Chapter 30 Plastic Surgery – Reconstructive Surgery (pages 553–573): Erik Ang and Woffles Wu
Chapter 31 Plastic Surgery – Aesthetic Surgery (pages 575–589): Woffles Wu and Erik Ang
Chapter 32 Renal Transplantation (pages 593–603): Vathsala Anantharaman
Chapter 33 Wound Healing (pages 607–626): Colin Song and Edwin Chan
Chapter 34 Palliative Care (pages 627–645): Robert S. Krouse and David Casarett
Chapter 35 Complementary Medicine (pages 647–668): Ping?Chung Leung
Chapter 36 Cluster Randomized Trials in Health Care Research (pages 669–680): Randall D. Cebul, Neal V. Dawson and Thomas E. Love
Chapter 37 Nursing (pages 681–697): Nicola Crichton
Chapter 38 Clinical Trials in Paediatrics (pages 699–710): Johan P. E. Karlberg
Chapter 39 Clinical Trials Involving Older People (pages 711–722): Carol Jagger and Antony J. Arthur
Chapter 40 Clinical Trials in Rare Diseases (pages 723–734): Simon Day

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